Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif
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چکیده
منابع مشابه
DNA-templated synthesis of trimethine cyanine dyes: a versatile fluorogenic reaction for sensing G-quadruplex formation.
It has been known for several decades that G-rich nucleic acid sequences have a propensity to fold into highly stable four-stranded structures in vitro in the presence of physiological cations, notably K and Na. Such structures, termed quadruplexes, have had their biological significance demonstrated for a number of processes. For example, it has been shown that the single-stranded 3’-end of te...
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2018
ISSN: 2041-1723
DOI: 10.1038/s41467-018-06942-3